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Yan J, Peng Y, Huang S, Fei W, Chen Y, Zheng C, et al

The Na + pump (or Na + /K + -ATPase), which uses about one fourth of the bodys ATP production, is the principal driving force for secondary active transport

Curr Opin Physiol 12:3943

Generally, compounds of the Formula I, may be prepared by standard solution phase or solid-phase synthesis from commercially available inputs by procedures well established in the art